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Sinovac, one of three Chinese vaccines in the last stages of testing, is expecting interim data as soon as November from its Phase 3 trial of almost 10,000 people in Brazil.
The idea of challenge trials has gained momentum as the pathogen has spread around the world, but such tests exposing healthy people to the coronavirus also raise ethical questions.
About 700 million vaccine doses should be available by April. The vaccine candidates that are furthest along in development will need a two-dose regimen, CDC chief Redfield said.
Guidelines released by the Central Drugs Standard Control Organisation say clinical data generated outside India will be studied to determine the safety & effectiveness of the vaccine.
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After safety reviews, Oxford says there is insufficient evidence to say for certain that neurological symptoms developed by volunteers were or were not related to the vaccine.
Microbiologist from the University of Hong Kong, Yuen Kwok-yung, said the vaccine stimulates the natural infection pathway of respiratory viruses to activate the immune response.
AstraZeneca CEO Pascal Soriot sought to reassure investors after the Oxford vaccine trial was halted due to a person in the UK falling sick, triggering a review of safety data.
9 Covid vaccine developers signed a pledge saying they won't submit their inoculations for Food & Drug Administration approval until they show safety & efficacy in late-stage trial.
The first results showing whether a vaccine can stop people from getting the virus could come by mid-September from AstraZeneca.