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Friday, April 17, 2026
TopicClinical trials

Topic: clinical trials

Drug from flowering plant holds promise in low-cost treatment of heart ailment

Trials show that digitoxin—active ingredient in foxglove—lowered mortality & hospitalisation in patients with reduced heart-pumping function, insufficient emptying of left ventricle.

To ease launch of generics & push clinical trials of novel therapies, govt moves to amend drug rules

Proposed amendments to New Drugs and Clinical Trial Rules will scrap test licences, cut application processing time. Move part of govt effort to establish India as hub for pharma R&D.

Experimental drug shows promise in treatment of hard-to-control high blood pressure

AstraZeneca’s experimental drug baxdrostat cut systolic BP by nearly 10 mmHg in a late-stage trial, offering hope to patients at a high risk of heart attacks, among others.

No local clinical trial waiver despite change in rules, drugmakers knock on health ministry’s door

Drug regulator through executive order issued last August paved way for direct launch of certain categories of drugs approved in select countries by means of local clinical trials waiver.

What if 10% of global clinical trials included African patients? It could benefit society, economy

Clinical studies to assess the treatment of schizophrenia with paliperidone palmitate in Rwanda were pivotal to catalysing research and development in other mental health areas.

Govt notifies rule for rapid launch of breakthrough drugs in India, bypassing local clinical trials

In an executive order, the DGCI has specified a list of countries under rule 101 of New Drugs and Clinical Trials Rules, 2019. List includes US, UK & EU, among others.

2 Alzheimer’s drugs have shown ‘promising’ results in trials. Why researchers are reacting with caution

After Lecanemab, a monoclonal antibody medication for Alzheime's, Eli Lilly and Co. too reported promising phase 3 trial results of its drug, Donanenab, for the disease.

New drug for acute leukaemia leads 53% to complete or partial remission in US trials

Revumenib found to be promising in 2 studies by US researchers published in 'Nature' Wednesday. Leukaemia accounted for nearly 4% of global cancer deaths in 2020.

No animal testing, human volunteers—how new-age ‘in silico’ trials will make drugs cheaper

Drug and medical device development through clinical trials can cost anywhere between $50 million to $1 billion. Computer-based testing can change that.

Lesson learnt from Covid, ICMR works to develop phase I clinical trial sites at govt institutes

Scientists say pandemic underlined need for speedy clinical trials, but most phase I units are in private sector. They urge trial sites in govt sector too, so focus is on public health, not profit.

On Camera

The Delimitation Dilemma—What Southern politicians should be bargaining for

Instead of fighting the inevitable population shift, southern leaders should seek to integrate migrants and preserve their local influence.

Indian LNG importers accelerate spot market purchases as prices dip

The purchases mark a turnaround after Indian buyers had earlier limited spot buying and canceled tenders because offers were too expensive.

Why Siliguri Corridor is strategically important for India & how it is being secured | Cut The Clutter

This special edition of Cut The Clutter, straight from the Siliguri corridor, details the strategic importance of the narrow strip of land in West Bengal, and how it’s a vital link connecting the Northeast to the rest of India.

The world’s in a flux. India must reform, consolidate & build a strong economy

We now live in a world order that will keep shifting. India must use this window. This also means we remain disciplined enough not to be knee-jerked into reacting to what Pakistan sees as its moment in the sun.