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Tuesday, December 2, 2025
TopicClinical trials

Topic: clinical trials

Drug from flowering plant holds promise in low-cost treatment of heart ailment

Trials show that digitoxin—active ingredient in foxglove—lowered mortality & hospitalisation in patients with reduced heart-pumping function, insufficient emptying of left ventricle.

To ease launch of generics & push clinical trials of novel therapies, govt moves to amend drug rules

Proposed amendments to New Drugs and Clinical Trial Rules will scrap test licences, cut application processing time. Move part of govt effort to establish India as hub for pharma R&D.

Experimental drug shows promise in treatment of hard-to-control high blood pressure

AstraZeneca’s experimental drug baxdrostat cut systolic BP by nearly 10 mmHg in a late-stage trial, offering hope to patients at a high risk of heart attacks, among others.

No local clinical trial waiver despite change in rules, drugmakers knock on health ministry’s door

Drug regulator through executive order issued last August paved way for direct launch of certain categories of drugs approved in select countries by means of local clinical trials waiver.

What if 10% of global clinical trials included African patients? It could benefit society, economy

Clinical studies to assess the treatment of schizophrenia with paliperidone palmitate in Rwanda were pivotal to catalysing research and development in other mental health areas.

Govt notifies rule for rapid launch of breakthrough drugs in India, bypassing local clinical trials

In an executive order, the DGCI has specified a list of countries under rule 101 of New Drugs and Clinical Trials Rules, 2019. List includes US, UK & EU, among others.

2 Alzheimer’s drugs have shown ‘promising’ results in trials. Why researchers are reacting with caution

After Lecanemab, a monoclonal antibody medication for Alzheime's, Eli Lilly and Co. too reported promising phase 3 trial results of its drug, Donanenab, for the disease.

New drug for acute leukaemia leads 53% to complete or partial remission in US trials

Revumenib found to be promising in 2 studies by US researchers published in 'Nature' Wednesday. Leukaemia accounted for nearly 4% of global cancer deaths in 2020.

No animal testing, human volunteers—how new-age ‘in silico’ trials will make drugs cheaper

Drug and medical device development through clinical trials can cost anywhere between $50 million to $1 billion. Computer-based testing can change that.

Lesson learnt from Covid, ICMR works to develop phase I clinical trial sites at govt institutes

Scientists say pandemic underlined need for speedy clinical trials, but most phase I units are in private sector. They urge trial sites in govt sector too, so focus is on public health, not profit.

On Camera

RSS is warming up to Yogi Adityanath. CM has many more boxes to tick

It’s not just the Opposition parties Yogi Adityanath has to contend with. His detractors within the BJP are no less formidable.

Modi govt’s PM internship scheme saw high attrition in Year 1. Just 30% joined, 41% quit midway

According to government reply in Lok Sabha, the pilot phase of PMIS is being used to test concepts, strategies and systems before a full-scale implementation of the scheme.

After Op Sindoor, India goes in for more Heron Mk IIs; Israel frontrunner for mega MALE drones deal

Order for 87 MALE drones will be split between 2 Indian firms in 64:36 ratio to ensure there are 2 independent manufacturing lines with at least 60% indigenous components.

Gaali cricket: Bavuma stands tall, India’s Test ego cut to size

The India-South Africa series-defining fact is the catastrophic decline of Indian red ball cricket where a visiting team can mock us with the 'grovel' word.