The Centers for Disease Control and Prevention is the national public health agency of the United States | Wikimedia commons
The Centers for Disease Control and Prevention is the national public health agency of the United States | Wikimedia commons
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New Delhi: An analysis of all those above 16 years who contracted Covid-19 in Los Angeles between 1 May and 25 July has revealed that unvaccinated people are 4.9 times more likely to get the disease and 29.2 times more likely to be hospitalised. 

The analysis was done by the Centers for Disease Control (CDC). This not only makes a very powerful case for the use of vaccinations to prevent serious disease but also shows that vaccines do reduce to a significant extent the chances of getting the infection.

“During May 1–July 25, 2021, among 43,127 SARS-CoV-2 infections in residents of Los Angeles County, California, 10,895 (25.3%) were in fully vaccinated persons, 1,431 (3.3%) were in partially vaccinated persons, and 30,801 (71.4%) were in unvaccinated persons. On July 25, infection and hospitalisation rates among unvaccinated persons were 4.9 and 29.2 times, respectively, those in fully vaccinated persons. In July, when the Delta variant was predominant, cycle threshold values were similar for unvaccinated, partially vaccinated, and vaccinated persons,” says the early release report of the analysis. 

Participants were considered fully vaccinated only if they had been either given the second dose of a Pfizer or Moderna vaccine at least 14 days prior to infection or a dose of the Johnson and Johnson vaccine at least a fortnight ago. The J&J Janssen vaccine is a one-dose vaccine. 

Those who got the infection less than 14 days after the second dose were considered partially vaccinated and those who had received one dose of either vaccine and had got the infection within the next fortnight, were considered, for the purpose of the analysis, unvaccinated. 

Hospitalisations were categorised as linked to Covid if they had happened within 14 days of diagnosis and all deaths that happened within 60 days of infection were counted as deaths because of Covid.

Half of LA’s residents were fully vaccinated.

Also read: New hurdle in India’s TB fight — states left with machines they can’t use

The study

By the time the data collection for the study had been concluded, 51 per cent LA residents had been fully vaccinated. 

“Among fully vaccinated persons on July 25, 55.2% had received the Pfizer-BioNTech vaccine, 28.0% had received the Moderna vaccine, and 16.8% had received the Janssen vaccine,” the study said. “Lower percentages of fully vaccinated persons were hospitalized (3.2%), were admitted to an intensive care unit (0.5%), and required mechanical ventilation (0.2%) compared with partially vaccinated persons (6.2%, 1.0%, and 0.3%, respectively) and unvaccinated persons (7.6%, 1.5%, and 0.5%, respectively).”

A total of 24 fully vaccinated people died of Covid. Investigations into the deaths revealed that six of them had conditions that affected their immunity such as HIV, cancer and transplants. 

During May-July, the predominant SARS-CoV-2 variant in LA was delta, which is highly transmissible. 

“Efforts to increase COVID-19 vaccination coverage, in coordination with other prevention strategies, are critical to preventing COVID-19–related hospitalizations and deaths,” the report said.

“Ongoing surveillance to characterize post vaccination infections, hospitalizations, and deaths will be important to monitor vaccine effectiveness, particularly as new variants emerge,” it added.

(Edited by Arun Prashanth)

Also read: 3rd wave could be worse than 2nd if vaccinations don’t pick up, bring 6L cases/day, govt warned


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