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China offers vaccines under development to Beijing workers amid fears of second wave

There are at least five Chinese vaccine candidates in the human trial stage, competing with products being developed by global names such as AstraZeneca Plc and Moderna Inc.

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Beijing: China is offering coronavirus vaccines under development to workers at state-owned companies in Beijing as the capital city experiences the nation’s biggest flare-up since Wuhan.

The government had earlier offered shots developed by China National Biotec Group Co., or CNBG, to state-run companies’ workers traveling overseas, Bloomberg reported last week. It’s now expanding that program to those firms’ employees living in Beijing districts currently under alert, or working in high-risk areas such as airports, according to people familiar with the matter who asked not to be identified as the offer hasn’t been made public.

The expanded voluntary inoculation may offer solace to workers facing growing risk as a potential second wave emerges in Beijing. It also puts to the test CNBG’s experimental shots amid a global race to find a successful vaccine to the deadly pathogen.

There are at least five Chinese vaccine candidates in the human trial stage, competing with products being developed by global pharmaceutical companies such as AstraZeneca Plc and Moderna Inc. that can bring an end to the pandemic and allow countries to reopen more fully after economically punishing lockdowns and travel curbs.

The new cluster, which emerged from Beijing’s largest wholesale fruit and vegetable market, has grown to more than 175 infections in a week and spread to at least four other Chinese provinces. While the country’s chief epidemiologist said the peak of the outbreak has passed, cases are expected to continue spreading.

The State-owned Assets Supervision and Administration Commission, which oversees China’s government-run companies, didn’t respond to a Bloomberg query. A spokeswoman at CNBG said the company has no information about this expanded inoculation and declined to comment further.

Besides being potentially protected against the virus, those volunteering will also help generate data on the shots’ efficacy against the novel pathogen that has sickened over 8.3 million people and killed more than 448,000 worldwide.

It isn’t yet known whether CNBG’s vaccines, which employ a dead strain of the novel coronavirus to elicit an immune response from the body, can prevent the infection.

Final Hurdle

CNBG said that one of the two experimental shots has been found to be generally safe and able to generate neutralizing antibodies, which could latch onto the virus to prevent it from invading cells. Their ability to prevent infection will only be clear in Phase III trials — the final hurdle to clear for securing marketing approval — in which thousands of people take the shot to see how effective it is in an active outbreak environment.

Chinese developers were previously concerned that they could not effectively conduct Phase III trials within the country as cases had seemingly dwindled nationwide. But if the resurgence of infections in Beijing isn’t brought under control, it could prompt researchers to consider the possibility of trials at home.

It’s uncertain how many employees of state-run firms traveling overseas or those in Beijing have taken up the offer, and whether they will be tracked for adverse reactions and their immune response. –Bloomberg


Also read: Beijing’s second coronavirus wave has been contained, says China’s chief epidemiologist


 

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