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Wednesday, July 23, 2025
TopicGene therapy

Topic: gene therapy

It’s official: New object zipping through our solar system is the 3rd known interstellar visitor

ScientiFix, our weekly feature, offers you a summary of the top global science stories of the week, with links to their sources.

AI-enabled DNA ‘switches’ can now control gene functions in tissues, organs

ScientiFix, our weekly feature, offers you a summary of the top global science stories of the week, with links to their sources.

A lethal fungus has wiped out bats in some US counties & it led to increased infant deaths

ScientiFix, our weekly feature, offers you a summary of the top global science stories of the week, with links to their sources.

‘Genetic scissors’ — India using same tech to find sickle cell cure as gene therapy approved by US FDA

FDA-approved Casgevy & Lyfgenia made from patients’ blood stem cells which are modified and given back as single-dose infusion. India ‘in preclinical stage’ of trial of similar therapy.

Cure for sickle cell disease on the horizon? US drug regulator is reviewing 2 new gene therapies

FDA is scheduled to review gene therapies from two American companies — Vertex Pharmaceuticals & Bluebird Bio Inc. If approved, therapies could mean a breakthrough for curing SCD.

Tweak norms on ‘biosimilars’ to make new life-saving drugs cheaper — patient rights groups to govt

Biosimilars are generic equivalents of biologic drugs, a new class of medicines that include therapeutics based on large molecules, such as monoclonal antibodies & gene therapies.

New hope for HIV cure: Dual gene editing ‘eliminates’ infection, targets protein that helps virus enter body

US study published in Proceedings of the National Academy of Sciences. Therapy administered to mice engrafted with human T cells resulted in suppression of virus & elimination of HIV-1.

IIT Kanpur signs MoU with Reliance Life Sciences, hopes to ‘revolutionise’ gene therapy

Developed by professor Jayandharan Giridhara Rao and Shubham Maurya of IIT Kanpur, the licensed technology replaces faulty gene with functional version to treat genetic eye diseases.

New US-approved gene therapy for Haemophilia B world’s most expensive drug — $3.5 mn per dose

Hemgenix, manufactured by Australia's CSL Behring, is a one-time therapy, given through a single dose of IV infusion & was approved by US Food and Drug Administration this week.

Sickle cell disease could have a cure soon, gene therapy shows good results in clinical trial

Results of phase 1&2 of 'LentiGlobin' therapy's trial, published by US researchers in NEJM, say durability remains to be seen. Oral pills more helpful for patients in Africa, India.

On Camera

Bihar mimics 19th-century American South. Citizenship is now weaponised to exclude voters

Disenfranchisement by institutional fiat is profoundly undemocratic. The effect of the ECI's new documentary process in Bihar will tilt the scales in favour of the BJP.

India-US set to ink mini trade deal soon, reach understanding on agricultural & dairy products

Mini deal will likely see no cut in 10% baseline tariff on Indian exports announced by Trump on 2 April, it is learnt, but additional 26% tariffs are set to be reduced.

Not just AK-203, India & Russia to jointly manufacture AK-19 and PPK-20 for domestic use and export 

India-Russia JV is also racing to deliver 7,000 more AK-203 assault rifles by 15 Aug. These are currently being made with 50% indigenisation and this will surge to 100% by 31 December.

Strategic partner one day, tactical nightmare the next: India’s learning Trumplomacy the hard way

Public, loud, upfront, filled with impropriety and high praise sometimes laced with insults. This is what we call Trumplomacy. But the larger objective is the same: American supremacy.