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Thursday, August 14, 2025
TopicGene therapy

Topic: gene therapy

It’s official: New object zipping through our solar system is the 3rd known interstellar visitor

ScientiFix, our weekly feature, offers you a summary of the top global science stories of the week, with links to their sources.

AI-enabled DNA ‘switches’ can now control gene functions in tissues, organs

ScientiFix, our weekly feature, offers you a summary of the top global science stories of the week, with links to their sources.

A lethal fungus has wiped out bats in some US counties & it led to increased infant deaths

ScientiFix, our weekly feature, offers you a summary of the top global science stories of the week, with links to their sources.

‘Genetic scissors’ — India using same tech to find sickle cell cure as gene therapy approved by US FDA

FDA-approved Casgevy & Lyfgenia made from patients’ blood stem cells which are modified and given back as single-dose infusion. India ‘in preclinical stage’ of trial of similar therapy.

Cure for sickle cell disease on the horizon? US drug regulator is reviewing 2 new gene therapies

FDA is scheduled to review gene therapies from two American companies — Vertex Pharmaceuticals & Bluebird Bio Inc. If approved, therapies could mean a breakthrough for curing SCD.

Tweak norms on ‘biosimilars’ to make new life-saving drugs cheaper — patient rights groups to govt

Biosimilars are generic equivalents of biologic drugs, a new class of medicines that include therapeutics based on large molecules, such as monoclonal antibodies & gene therapies.

New hope for HIV cure: Dual gene editing ‘eliminates’ infection, targets protein that helps virus enter body

US study published in Proceedings of the National Academy of Sciences. Therapy administered to mice engrafted with human T cells resulted in suppression of virus & elimination of HIV-1.

IIT Kanpur signs MoU with Reliance Life Sciences, hopes to ‘revolutionise’ gene therapy

Developed by professor Jayandharan Giridhara Rao and Shubham Maurya of IIT Kanpur, the licensed technology replaces faulty gene with functional version to treat genetic eye diseases.

New US-approved gene therapy for Haemophilia B world’s most expensive drug — $3.5 mn per dose

Hemgenix, manufactured by Australia's CSL Behring, is a one-time therapy, given through a single dose of IV infusion & was approved by US Food and Drug Administration this week.

Sickle cell disease could have a cure soon, gene therapy shows good results in clinical trial

Results of phase 1&2 of 'LentiGlobin' therapy's trial, published by US researchers in NEJM, say durability remains to be seen. Oral pills more helpful for patients in Africa, India.

On Camera

Asim Munir wants to be guardian of the Middle East. He’s fated to fail at home

Countering insurgency needs the Pakistan Army to demonstrate a political will that ties leaders at the centre with those in the borderlands. But it may not have the imagination.

Slashing GST on waste can unlock Rs 1.8 lakh crore, high tax hurting circular economy goals—CSE

Centre for Science and Environment in new report makes case for rationalising GST on waste material, saying most informal operators can’t afford high tax & it also hinders recycling.

India, US troops to undertake joint military exercise next month, first after Op Sindoor

21st edition of annual joint military exercise will be held from 1 to 16 September, aimed at sharing military tech, operational best practices & disaster relief coordination methods.

Modi’s ready to risk it all for farmers. Farm reform can answer Trump with new Green Revolution

Standing up to America is usually not a personal risk for a leader in India. Any suggestions of foreign pressure unites India behind who they see as leading them in that fight.