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Tuesday, March 31, 2026
TopicGene therapy

Topic: gene therapy

India approves Zolgensma, one of world’s costliest drugs. Why it’s sparked hope, but also concern

Zolgensma is the only drug that promises a cure for Spinal Muscular Atrophy, provided it is administered to affected children before the symptoms appear.

It’s official: New object zipping through our solar system is the 3rd known interstellar visitor

ScientiFix, our weekly feature, offers you a summary of the top global science stories of the week, with links to their sources.

AI-enabled DNA ‘switches’ can now control gene functions in tissues, organs

ScientiFix, our weekly feature, offers you a summary of the top global science stories of the week, with links to their sources.

A lethal fungus has wiped out bats in some US counties & it led to increased infant deaths

ScientiFix, our weekly feature, offers you a summary of the top global science stories of the week, with links to their sources.

‘Genetic scissors’ — India using same tech to find sickle cell cure as gene therapy approved by US FDA

FDA-approved Casgevy & Lyfgenia made from patients’ blood stem cells which are modified and given back as single-dose infusion. India ‘in preclinical stage’ of trial of similar therapy.

Cure for sickle cell disease on the horizon? US drug regulator is reviewing 2 new gene therapies

FDA is scheduled to review gene therapies from two American companies — Vertex Pharmaceuticals & Bluebird Bio Inc. If approved, therapies could mean a breakthrough for curing SCD.

Tweak norms on ‘biosimilars’ to make new life-saving drugs cheaper — patient rights groups to govt

Biosimilars are generic equivalents of biologic drugs, a new class of medicines that include therapeutics based on large molecules, such as monoclonal antibodies & gene therapies.

New hope for HIV cure: Dual gene editing ‘eliminates’ infection, targets protein that helps virus enter body

US study published in Proceedings of the National Academy of Sciences. Therapy administered to mice engrafted with human T cells resulted in suppression of virus & elimination of HIV-1.

IIT Kanpur signs MoU with Reliance Life Sciences, hopes to ‘revolutionise’ gene therapy

Developed by professor Jayandharan Giridhara Rao and Shubham Maurya of IIT Kanpur, the licensed technology replaces faulty gene with functional version to treat genetic eye diseases.

New US-approved gene therapy for Haemophilia B world’s most expensive drug — $3.5 mn per dose

Hemgenix, manufactured by Australia's CSL Behring, is a one-time therapy, given through a single dose of IV infusion & was approved by US Food and Drug Administration this week.

On Camera

How West Asia crisis can play out for PM Modi and BJP in Assembly polls

While the Russia-Ukraine war saw the BJP projecting PM Modi as a ‘vishwaguru’ who could end international conflicts, the party has made a nuanced shift in its electoral strategy vis-à-vis the West Asia war.

Foreign investors dump record $12 bn India stocks in March on war

Soaring energy costs have hurt oil-importing Asian peers, but the scale of outflows from India points to already bearish global sentiment.

India developing lethal autonomous weapon systems, database of citizens’ crime risk—House Panel report

Report on impact of AI emergence—drawing upon depositions from several ministries—confirms that the developments come in the absence of AI laws or considerations over them.

Gulf war exposed India’s fragilities. It’s time for navel-gazing, in the national interest

It’s easy to understand why the government can’t speak the hard truth. When this war ends, as all wars do, India’s interests will lie with both the winner and the loser.