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Saturday, January 3, 2026
TopicFixed-dose combination drugs

Topic: fixed-dose combination drugs

Trial in India finds 2-drug combinations 5 times more effective than single pill in controlling hypertension

Amlodipine & perindopril, amlodipine & indapamide, and perindopril & indapamide achieved blood pressure control in 70 percent of patients to less than 140/90 mm Hg in six months.

Health ministry bans FDCs every few years. Ask how they enter the market in the first place

The medical rationale behind fixed-dose combination drugs soon gave into commercial interests that cared little for the health of patients. Government's only response has been to keep issuing ban orders since 1983.

Over 60% drug cocktails used for mental illnesses in India unapproved by apex regulator, finds study

Study by researchers from UK, India & Qatar was published this month, suggests unapproved fixed-dose combination drugs should be withdrawn and no longer manufactured.

1st US FDA-approved drug invented in India set for local launch as part of combination antibiotic

Combination of enmetazobactam, invented by scientists associated with Chennai-based pharma firm Orchid Pharma in 2008, and antibiotic cefipime is used to treat severe bacterial infection.

After prohibiting popular FDC for kids under 4, drug regulator scrutinises other cold & cough remedies

Following December notice prohibiting combination of chlorpheniramine maleate & phenylephrine hydrochloride, CDSCO has ‘decided to rope in paediatricians to review other permitted FDCs’.

Drug regulator gives conditional nod for sale of 5 FDCs, seeks efficacy & safety data for 3 of them

Popular brands using combinations under the scanner include D Cold Total and Dolo Cold. The five FDCs are part of 344 drug combinations that the government had first banned in 2016.

70% of antibiotic fixed-dose combination drugs sold in India unapproved or banned, finds study

Govt’s moves to curb irrational fixed-dose combinations may have been insufficient & lack enforcement, say researchers. Study published in Journal of Pharmaceutical Policy and Practice.

On Camera

India’s urban co-op banks are turning the page—crisis to cautious revival, one metric at a time

With bad loans shrinking & capital buffers stronger, urban co-op banks’ new umbrella body NUCFDC is now prioritising rollout of digital transformation.

Greece looking at TATA’s WhAP infantry combat vehicle for army procurement

If deal goes through, Greece will be 2nd foreign country to procure vehicle. Morocco was first; TATA Group has set up manufacturing unit there with minimum 30 percent indigenous content.

A year-end Mea Culpa in National Interest—The Army-Islam combo doesn’t kill democracy

Many of you might think I got something so wrong in National Interest pieces written this year. I might disagree! But some deserve a Mea Culpa. I’d deal with the most recent this week.