Pfizer and BioNTech on track to potentially be the first to show the efficacy of a Covid-19 vaccine, in an environment of intense scrutiny over every possible complication.
Covid-19 vaccines under development are injectable. Scientists are hoping for better immune responses with inhaled ones that directly target the nose & mouth.
According to the CDSCO panel, the pharma company has to conduct both phase 2 and 3 clinical trials and cannot directly hold phase 3 trial for the vaccine in India, a source said.
The phase 1 and 2 trials resumed after the Japanese regulator gave the go-ahead. Trials in the UK, Brazil, South Africa and India had already restarted in recent weeks.
Sinovac, one of three Chinese vaccines in the last stages of testing, is expecting interim data as soon as November from its Phase 3 trial of almost 10,000 people in Brazil.
The idea of challenge trials has gained momentum as the pathogen has spread around the world, but such tests exposing healthy people to the coronavirus also raise ethical questions.
About 700 million vaccine doses should be available by April. The vaccine candidates that are furthest along in development will need a two-dose regimen, CDC chief Redfield said.
Guidelines released by the Central Drugs Standard Control Organisation say clinical data generated outside India will be studied to determine the safety & effectiveness of the vaccine.
SEBI probe concluded that purported loans and fund transfers were paid back in full and did not amount to deceptive market practices or unreported related party transactions.
A common thread runs through the memories of soldiers of the 1965 war—ingenuity, courage and camaraderie that withstood an apparently technologically superior foe.
Many really smart people now share the position that playing cricket with Pakistan is politically, strategically and morally wrong. It is just a poor appreciation of competitive sport.
COMMENTS