Pfizer and BioNTech on track to potentially be the first to show the efficacy of a Covid-19 vaccine, in an environment of intense scrutiny over every possible complication.
Covid-19 vaccines under development are injectable. Scientists are hoping for better immune responses with inhaled ones that directly target the nose & mouth.
According to the CDSCO panel, the pharma company has to conduct both phase 2 and 3 clinical trials and cannot directly hold phase 3 trial for the vaccine in India, a source said.
The phase 1 and 2 trials resumed after the Japanese regulator gave the go-ahead. Trials in the UK, Brazil, South Africa and India had already restarted in recent weeks.
Sinovac, one of three Chinese vaccines in the last stages of testing, is expecting interim data as soon as November from its Phase 3 trial of almost 10,000 people in Brazil.
The idea of challenge trials has gained momentum as the pathogen has spread around the world, but such tests exposing healthy people to the coronavirus also raise ethical questions.
About 700 million vaccine doses should be available by April. The vaccine candidates that are furthest along in development will need a two-dose regimen, CDC chief Redfield said.
Guidelines released by the Central Drugs Standard Control Organisation say clinical data generated outside India will be studied to determine the safety & effectiveness of the vaccine.
If this step even partially achieves its desired results, there will be so much dislocation in the country’s economic structure as to prove a national calamity, advocate AG Mulgaokar wrote in 1969.
Recommendations appear in Niti Aayog’s Tax Policy Working Paper Series–II. It says there is a need to shift away from fear-based enforcement to trust-based governance.
In service with the British military since 2019, it is also known as the Martlet missile. Ukrainians have also deployed these missiles against Russian troops.
Education, reservations, govt jobs are meant to bring equality and dignity. That we are a long way from that is evident in the shoe thrown at the CJI and the suicide of Haryana IPS officer. The film Homebound has a lesson too.
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