Pfizer and BioNTech on track to potentially be the first to show the efficacy of a Covid-19 vaccine, in an environment of intense scrutiny over every possible complication.
Covid-19 vaccines under development are injectable. Scientists are hoping for better immune responses with inhaled ones that directly target the nose & mouth.
According to the CDSCO panel, the pharma company has to conduct both phase 2 and 3 clinical trials and cannot directly hold phase 3 trial for the vaccine in India, a source said.
The phase 1 and 2 trials resumed after the Japanese regulator gave the go-ahead. Trials in the UK, Brazil, South Africa and India had already restarted in recent weeks.
Sinovac, one of three Chinese vaccines in the last stages of testing, is expecting interim data as soon as November from its Phase 3 trial of almost 10,000 people in Brazil.
The idea of challenge trials has gained momentum as the pathogen has spread around the world, but such tests exposing healthy people to the coronavirus also raise ethical questions.
About 700 million vaccine doses should be available by April. The vaccine candidates that are furthest along in development will need a two-dose regimen, CDC chief Redfield said.
Guidelines released by the Central Drugs Standard Control Organisation say clinical data generated outside India will be studied to determine the safety & effectiveness of the vaccine.
Compassion and cohabitation with animals are ingrained in the Indian value system. A humane solution must be found for the rising conflict between man and free-range animals.
New bill aims to fix key issues with IBC 2016, including delays & patchy implementation, and protect creditors, with window for genuine promoters to retain control of their companies.
Three battalions are being deployed along northern frontier with China and Pakistan, one in the northeast and another on western front, ThePrint has learnt.
Putin sees this as a victory. Europeans have decided to deal with Trump on his terms for the sake of the larger Western alliance. We look at the lessons for us in India.
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